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Positive reaction to allergen

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Coccidioidin or spherulin skin test

Normal Values: No reaction (inflammation) to the microorganism is normal. What abnormal results mean: A positive reaction indicates there has been exposure to the microorganism. This test can be very helpful in diagnosing early infection, since the skin test can be positive 2-21 days after the onset of symptoms, even before a blood test is positive. A significant number of patients will have anergy, or will not respond to this test even when they have the disease. Text Continues Below There can be false-positives, in that there can be positive results when the patient has been exposed to histoplasma fungus or blastomyces fungus, but not coccidioides. A positive result may also reflect exposure to coccidioides in the distant past, rather than current infection.

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