Synovial biopsy

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Synovial biopsy

A synovial biopsy is the removal of a piece of tissue lining a joint. The tissue is called the synovial membrane.

Biopsy - synovial membrane

The test is usually done in the operating room with the use of arthroscopy.

The health care provider will inject a numbing medicine (local anesthetic) into the area. An instrument called a trocar is inserted into the joint space. This tool helps push fluid in and out of the area. A biopsy grasper is inserted through the trocar and turned to cut out a tissue segment.

The tools are removed. The biopsy site is cleaned. Pressure and a bandage are applied.

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Tell your health care provider:

• If you are pregnant
• If you have any drug allergies
• If you have bleeding problems
• What medications you are taking (including any herbal medicines and supplements)

With the local anesthetic, you will feel a prick and a burning sensation. As the trocar is inserted, there will be some discomfort.

Synovial biopsy helps diagnose gout, bacterial infections, or other infections, and may suggest the presence of inflammatory conditions such as autoimmune disorders.

Review Date: 07/28/2010
Reviewed By: Linda J. Vorvick, MD, MEDEX Northwest Division of Physician Assistant Studies, University of Washington School of Medicine; and C. Benjamin Ma, MD, Assistant Professor, Chief, Sports Medicine and Shoulder Service, UCSF Department of Orthopaedic Surgery. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.

A.D.A.M., Inc. is accredited by URAC, also known as the American Accreditation HealthCare Commission (www.urac.org).