Medical Health Encyclopedia

A major analysis of other conservative approaches found no significant relief from nonsteroidal anti-inflammatory drugs (NSAIDs), which include common pain relievers such as aspirin and ibuprofen (Advil). The same report also found no benefits from diuretics, which eliminate fluid, or a number of alternative methods, including magnet therapy, laser acupuncture, vitamin B6, exercise or chiropractic care. Other approaches that merit some research include omega-3 fatty acid and cognitive-behavioral therapy.

Underlying Conditions. It is important treat any underlying medical condition that might be causing carpal tunnel syndrome. For example, reducing inflammation in rheumatoid arthritis or other forms of inflammatory disorders that directly cause CTS is very helpful.

Treatments for diseases only associated with carpal tunnel, such as hypothyroid or diabetes may not be as effective for relieving CTS symptoms. Some interesting research involves injections of insulin into the median nerves of patients with type 2 diabetes mellitus who had mild to moderate CTS. Insulin has a nerve regenerating effect. In one study, after an initial steroid injection, seven weekly insulin injections proved significantly beneficial compared to placebo. Further research is needed on this therapy.

Wrist Splints

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Wrist splints are used to keep the wrist from bending. They are not as beneficial as surgery for patients with moderate to severe CTS, but they appear to be helpful in specific patients. In one study, the best success rates were in patients with mild to moderate nighttime symptoms of less than a year's duration. In selected patients, up to 80% reported fewer symptoms, usually within days of wearing the sprint.

Although typically the splint is worn at night or during sports, one 2000 study reported that wearing it full time is most beneficial. (In the study, few patients actually complied with the regimen and wore them full time, but any regular use appeared to improve nerve function and symptoms.) The splint is used for several weeks or months depending on the severity of the problem, and may be combined with hand and finger exercises. A 2005 study reported that a 6-week course of at-night splinting reduced symptom severity in people with CTS and that the benefits were still evident after 1 year.