 | | | | Medical Health Encyclopedia | |
Other NSAID said effects can include:
- Delayed emptying of the stomach, which could interfere with the actions of other drugs (elderly are at special risk)
- Dizziness
- Tinnitus (ringing in the ear)
- Headache
- Skin rash
- Confusion or bizarre sensation (in some higher-potency NSAIDs, such as indomethacin)
As with acetaminophen, high daily doses of aspirin have been associated with an increased risk of kidney failure, although the risk remains low in those with healthy kidney function. Kidney abnormalities have been reported in people taking other NSAIDs as well, which resolve when the drugs are withdrawn. Any sudden weight gain or swelling should be reported to a doctor. Anyone with kidney disease should avoid these drugs.
Diabetics taking oral hypoglycemics may need to adjust the dosage if they also need to take NSAIDs because of possible harmful interactions between the drugs.
Text Continues Below
Note: Some studies have reported that ibuprofen (but not other NSAIDs) may blunt the heart-protective effects of low-dose aspirin, Additional research is needed to confirm these findings.
NSAID-Induced Ulcers and Gastrointestinal Bleeding
Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs) is the second most common cause of ulcers. Ulcers caused by nonsteroidal anti-inflammatory drugs (NSAIDs) are more likely to bleed than those caused by the bacteria Heliobacter pylori.
NSAID-related bleeding and stomach problems may be responsible for 107,000 hospital admissions and 16,500 deaths each year. Those at high risk for bleeding include the elderly, anyone with a history of ulcers of gastointestinal bleeding, patients with serious heart conditions, people who abuse alcohol, and those on medications such anticoagulants (blood thinners), corticosteroids, or bisphosphonates (drugs used for osteoporosis).
|
|
|
.gif)
