Symptoms
Symptoms of localized scleroderma develop slowly. Diffuse and limited scleroderma symptoms may progress slowly or very rapidly.
Raynaud's Phenomenon
Raynaud's phenomenon is often the first manifestation of the scleroderma disease process. With this condition, small blood vessels constrict the arteries in the fingers, toes, ears, and even the nose.
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Typically, the fingers undergo three color changes.
- First, they become very pale.
- As the circulation is cut off, they turn a bluish color, usually in the top two sections of the second and third fingers.
- Finally, when blood returns the fingers become red.
- Tingling and pain may occur in the affected regions.
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Click the icon to see an image of raynaud's phenomenon. |
Attacks can occur several times a day and are often triggered or exacerbated by cold and relieved by warmth. In severe cases, cold may have little influence on whether the attacks occur or not. The syndrome may also be triggered by stress. In severe cases, if the circulation is cut off for prolonged periods, ulcers or even gangrene may develop.
It is important to note over 80% of cases of Raynaud's phenomenon are harmless. It is very common and occurs in 3% o 5% of the general population. This condition is more likely to be associated with scleroderma or some other connective tissue disease if it develops after age 30, if it is severe, and if it is accompanied by other symptoms (e.g., skin changes, arthritis).
Skin Changes
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