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Glucosamine. There have been some reports that glucosamine, an alternative remedy commonly used for osteoarthritis, may prevent migraine attacks. Some researchers theorize this substance may reduce inflammation that affects nerves involved in vascular headaches. Whether this agent has any effect on cluster headaches is unknown.

Additional Therapies. Many patients with cluster headaches try alternative remedies for relief of pain. Treatments may include acupuncture, herbs, chiropractic, homeopathic remedies, reflexology, hypnosis, spiritual therapies, massage, aromatherapy, relaxation techniques, and yoga. A 2002 survey of patients attending a headache clinic or support groups, however, did not find any of these alternative therapies to be consistently effective.

Treatment for Sleep Apnea

Patients with cluster headaches who suffer from daytime sleepiness should consider being evaluated for a possible diagnosis of sleep apnea. Anyone who has both should then strongly consider treatment for the apnea as possible therapy for cluster headaches.

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In some studies, patients with both cluster headaches and apnea who were treated with nasal continuous positive airway pressure (CPAP) experienced substantial reduction in the frequency and severity of cluster headaches. Currently, CPAP is the best treatment for many types of sleep apnea. It works in the following way:

  • The treatment employs a machine weighing about five pounds that fits on a bedside table.
  • A mask containing a tube connects to the device and fits over just the nose.
  • The machine supplies a steady stream of air through a tube and applies sufficient air pressure to prevent the tissues from collapsing during sleep.



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