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Brain Sees Reward Before Risk

Researchers learn how the brain processes risky behavior such as gambling

By Serena Gordon
HealthDay Reporter


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TUESDAY, Aug. 1 (HealthDay News) -- California researchers say they have pinpointed the area of the brain that governs gambling behaviors.

By using functional magnetic resonance imaging (fMRI), scientists at the California Institute of Technology, in Pasadena, confirmed that the "gambling" parts of the brain lie in the subcortical region, and there are pathways in the brain that weigh risk and reward.

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"We wanted to know what happens in the brain when one is faced with a probable reward and risk," said study co-author Kerstin Preuschoff, a doctoral student at the institute.

Preuschoff said that by understanding these pathways, scientists may be able to develop ways to treat those with impaired decision-making skills, such as gamblers, people with bipolar disorder, and schizophrenics.

The findings were expected to be published in the Aug. 3 issue of Neuron.

The study included 19 healthy adults between the ages of 18 and 30. Nine were female. All had no history of mental illness or gambling addiction.

Each participant was given an initial endowment of $25. While they were being scanned with fMRI -- which produces images of blood flow in the brain -- they were asked to bet $1 on whether or not the first or second card from a deck of 10 would be higher.

"They had to first place the bet without seeing the cards," explained Preuschoff. "Then, the expectation changes when they see the first card."

The researchers focused on the period after the study volunteers saw the first card, but before they'd seen the second card. It was during this period that they had enough information to more accurately assess the risk of the bet that they'd already placed, and to anticipate the reward of winning if they felt their card was a good one.

Interestingly, the study participants focused for a second solely on the anticipated reward.

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Copyright © 2006 ScoutNews LLC. All rights reserved.
Last updated 8/2/2006

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SOURCES: Kerstin Preuschoff, doctoral student, California Institute of Technology, Pasadena, Calif.; Eric Hollander, M.D., professor and chairman, psychiatry, Mount Sinai School of Medicine, New York City; Aug. 3, 2006, Neuron


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