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Stem Cell Technique Could Help Kids Avoid Root Canal


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Endodontists typically offer patients root canal to treat this condition. Root canal involves the use of dental instruments to remove the infected soft pulp tissue -- commonly referred to as "nerve" tissue -- located in the center of the tooth. The hollowed-out pulp chamber that once housed the extracted tissue is then filled and sealed to prevent re-infection or the spread of bacteria to other areas.

According to dental experts, the excised nerve tissue is not critical to normal oral function once adult teeth have matured, so removal of degenerated matter does not induce long-term problems.

However, nerve/pulp tissue is vital to the healthy development of teeth in children under the age of 16. The adult tooth-maturation process takes approximately three years to complete from the time a tooth first appears.

Text Continues Below



That means that in younger patients, root canal can stop this process and boost risks for dental complications, fractures, and even facial disfigurement.

But Huang's team knew that the pulp in maturing teeth is much richer in blood supply than that seen in adults. It also has a greater ability to regenerate itself compared to the pulp inside adult teeth. That's because stem cells inside children's teeth have the capacity to generate into the material that forms "dentin" -- the tooth's primary connective tissue.

So, would periodontitis treatments that allowed stem cells to stay in place and do their vital work leave kids with stronger teeth?

To find out, Huang's team tackled four cases of periodontitis in Taiwanese boys and girls between the ages of nine and 10 who were treated for the disease between 1988 and 2000.

In place of a root canal, the pulp chambers of the children's problem teeth were irrigated with about 20 ml of 2.5 percent sodium hypochlorite -- a chemical compound often used as a disinfectant and bleaching agent.

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Copyright © 2006 ScoutNews LLC. All rights reserved.
Last updated 12/21/2006

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SOURCES: George T.-J. Huang, DDS, endodontist, and associate professor, University of Maryland, College of Dental Surgery, Baltimore; Jim Crall, DDS, chairman, pediatric dentistry, University of California, Los Angeles; December 2006 Journal of Endodontics; Dec. 20, 2006, press release, University of Southern California


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