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Stem Cell Technique Could Help Kids Avoid Root Canal


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In a related study, a multi-national research team successfully regenerated tooth root and supporting periodontal ligaments to restore tooth function in an animal model. The breakthrough holds promise for clinical application in human patients, said the researchers, headed by Dr. Songtao Shi at the University of Southern California School of Dentistry.

Using stem cells taken from extracted wisdom teeth of 18- to 20-year-olds, the researchers created enough root and ligament structure to support a crown restoration in their animal model. The resulting tooth restoration closely resembled the original tooth in function and strength.

Shi said the hope is the research could one day benefit dental patients who are not appropriate candidates for dental implant therapy or would prefer living tissue derived from their own teeth.

Text Continues Below



The findings are published in the Dec. 20 inaugural issue of PLoS ONE.

More information

For additional information on periodontal disease, visit the American Academy of Periodontology.

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Copyright © 2006 ScoutNews LLC. All rights reserved.
Last updated 12/21/2006

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SOURCES: George T.-J. Huang, DDS, endodontist, and associate professor, University of Maryland, College of Dental Surgery, Baltimore; Jim Crall, DDS, chairman, pediatric dentistry, University of California, Los Angeles; December 2006 Journal of Endodontics; Dec. 20, 2006, press release, University of Southern California


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