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Page: << Prev | 1 | 2 | 3 Dr. Mark Fendrick, a professor of internal medicine at the University of Michigan School of Medicine, agreed. "If you have cardiovascular concerns and no gastrointestinal risk, I would avoid the cox-2 inhibitors like the plague," he said.
"If you had a prior ulcer and can't tolerate Tylenol, and are lucky enough not to have any cardiovascular risk, then I would lean toward a cox-2 inhibitor or a traditional NSAID and a proton pump inhibitor," Fendrick said. "If you have both risks, then I would use acetaminophen or low-dose narcotics or a more cardiac safe NSAID, like Naproxen, and a proton pump inhibitor."
More information
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For more information on cox-2 inhibitors, visit the U.S. Food and Drug Administration.
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Copyright © 2007 ScoutNews, LLC. All rights reserved.
Last updated 2/9/2007
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SOURCES: Loren Laine, M.D., professor of medicine, University of Southern California Keck School of Medicine, Los Angeles; Joost Drenth, M.D., Radboud University Nijmegen Medical Center, the Netherlands; Mark Fendrick, M.D., professor of internal medicine, University of Michigan School of Medicine, and professor of health management and policy, University of Michigan School of Public Health, Ann Arbor; James M. Scheiman, M.D., professor of medicine, University of Michigan Medical Center, Ann Arbor; Feb. 10, 2007, The Lancet
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