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Heart Experts Issue Guidelines on Use of Celebrex


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A number of studies have concluded that the use of cox-2 selective NSAIDs (designed to reduce gastrointestinal side effects caused by traditional NSAIDs) increase the likelihood of cardiovascular disease complications in people with, or at risk for, heart disease, Antman said.

A meta-analysis found that cox-2 selective NSAIDs were associated with an 86 percent increased risk of heart attack, said the scientific statement, which also noted that two non-cox-2 NSAID drugs -- diclofenac and ibuprofen -- may also increase the risk of heart problems.

In recent years, the U.S. Food and Drug Administration has added warning statements to NSAIDs (with the exception of aspirin) about an increased risk of cardiovascular events when taking these drugs, the scientific statement noted.

Text Continues Below



More information

MedlinePlus has more about NSAIDs.

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-- Robert Preidt

Copyright © 2007 ScoutNews, LLC. All rights reserved.
Last updated 2/26/2007

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SOURCE: American Heart Association, news release, Feb. 26, 2007


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