Are Common Chemicals Feeding Obesity Epidemic?

Study suggests exposure to phthalates linked to abdominal fat, insulin resistance in men

By Amanda Gardner
HealthDay Reporter

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THURSDAY, March 15 (HealthDay News) -- Exposure to a class of chemicals commonly found in soap and plastics could be fueling the obesity epidemic by contributing to abdominal obesity and insulin resistance in men, a new study suggests.

The chemicals, known as phthalates, have already been implicated in male reproductive problems including low sperm counts and low testosterone levels. However, it's too soon to know whether they are actually causing these health problems, cautioned the researchers and others.

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"It's premature for folks to be alarmed," said study author Dr. Richard Stahlhut, a resident in preventive medicine at the University of Rochester School of Medicine & Dentistry in New York.. "What is more alarming is the reason we are doing studies like this. Another study showed that testosterone levels had dropped about 22 percent in men, and that sperm counts had dropped to levels that are considered subfertile or infertile."

"It's an important observation that chemical exposures could be contributing to obesity and diabetes in the general population," added Dr. Ted Schettler, science director for the Science and Environmental Health Network. "This is one more example of a family of chemicals that may be contributing to this problem, but this study has obvious limits that the authors acknowledge in great detail."

The study was published in the March 14 online edition of Environmental Health Perspectives.

Phthalates have been widely used for more than half a century in everything from paint to time-released medicines, but only recently have they become a topic of concern. Animal studies show that phthalates decrease testosterone levels while human studies have found that phthalates are associated with poor sperm quality in men.

This study follows up on other studies that correlated abnormal sperm counts and low testosterone levels with phthalates. Men with low testosterone levels develop abdominal obesity and insulin resistance, so these authors speculated that phthalates might be behind the depressed testosterone levels.

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