Next Generation of Stents Responds to Problems

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There were no cases of stent thrombosis or restenosis, Serruys added.

Serruys noted that the length of time for the stent to dissolve isn't yet known, because that was the first time it has been used in people.

"In animals, it takes about 18 months," he said.

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It will be years before such a stent is used in regular treatment, Serruys added. In addition, problems with the stent have sent the researchers back to the drawing board to redesign it.

In another study, Danish researchers showed that once blood-thinning therapy is stopped, drug-eluting stents could be linked to a higher risk of heart attack and stent thrombosis than bare metal stents are.

In the trial, led by Dr. Michael Maeng, from the department of cardiology at Aarhus University Hospital, Skejby, 12,395 patients received either drug-eluting stents or bare metal stents.

"Recent reports have indicated a potential increased risk of stent thrombosis, myocardial infarction and death with the use of drug-eluting stents," Maeng said.

Over 12 months, Maeng's group found that, while the rates of restenosis were significantly lower among patients receiving drug-eluting stents, the rates of heart attack and stent thrombosis were similar in both groups.

However, between 12 and 15 months, after blood-thinning drugs were stopped, there was a small but significant trend toward a higher risk of heart attack and stent thrombosis among patients who received drug-eluting stents.

"The follow-up period of 15 months may be insufficient to quantify risk with drug-eluting stents," Maeng said. "Drug-eluting stents are as safe as bare metal stents, at least up to 15 months after implantation."

More information

For more information on stents, visit the American Heart Association.

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