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Herbal Extract Shows Some Benefit for Heart Failure


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However, WS 1442 was not effective when it came to death due to progressive heart failure, fatal heart attack, non-fatal heart attack and hospitalization because of heart failure.

"We did not meet the primary endpoint," the researcher said.

Holubarsch cautioned that the findings were preliminary. "We cannot prove that the compound extends life of these patients, but I think it's promising," he said.

Text Continues Below



One heart expert said he thought that because the study failed to meet the primary goal, it raises a red flag.

"If the specified primary endpoint did not have a significant impact, any observation from a secondary endpoint should be considered hypothesis-generating, rather than evidence that this therapy is beneficial," said Dr. Gregg Fonarow, a cardiologist at the University of California, Los Angeles.

"As this is a single, modestly sized trial, these finding will require confirmation in other independently conducted, randomized, double-blind, placebo-controlled trials," he said.

More information

For more information on heart failure, visit the American Heart Association.

Page:  << Prev | 1 | 2

Copyright © 2007 ScoutNews, LLC. All rights reserved.
Last updated 3/28/2007

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SOURCES: Christian J.F. Holubarsch, M.D., Median Kliniken Hospitals, Bad Krozingen, Germany; Gregg Fonarow, M.D., professor of clinical medicine, University of California, Los Angeles; March 27, 2007, presentation, American College of Cardiology annual meeting, New Orleans


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