Antidepressants May Not Help Fight Bipolar Disorder

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Another expert said the study could change doctors' thinking.

"Treatment needs to be individualized, but, for the vast majority of patients, antidepressants don't offer critical benefit and may carry significant risk," said Dr. Richard Weisler, adjunct professor of psychiatry at the University of North Carolina at Chapel Hill and adjunct associate professor of psychiatry at Duke University Medical Center in Durham, N.C.

Other studies have suggested that antidepressants do come with their own dangers, and, "if you've got those risks and little benefit, then we need to be rethinking how most clinicians are actually treating bipolar in this country," Weisler said.

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As early as next week, results regarding the effects of psychosocial treatments used in the trial will be released. And there will likely be many more papers from this set of data, Sachs said.

More information

For more on bipolar illness, head to the National Institute of Mental Health.

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