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Prostate Cancer Gene Also Raises Colon Cancer Risk


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While intriguing, experts agreed that the finding does not have immediate implications for the detection, prevention and treatment of colorectal cancer, which kills more than 51,000 Americans each year, according to the American Cancer Society.

"These are encouraging findings, but obviously we need a lot more information about the genetic implications," said Dr. Durado Brooks, the society's director of prostate and colorectal cancer. Genetic tests that might assess people's risk or help in cancer diagnosis are still years away, and, for now, the new finding "will not in any way significantly alter clinical practice," he said.

Still, the assembled experts agreed that clinical application remains the ultimate goal of their research efforts.

Text Continues Below



Ideally, Dunlop said, tests might someday be developed to spot genes like rs6983267, "such that you could tailor interventions such as more intensive [patient] surveillance and even prevention," he said. "This is big step forward, but there is more to come."

More information

Find out more about colorectal cancer at the American Cancer Society.

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Copyright © 2007 ScoutNews, LLC. All rights reserved.
Last updated 7/9/2007

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SOURCES: July 6, 2007, Nature Genetics news conference, with Malcolm Dunlop, M.D., researcher, Cancer Research UK, and head, Colon Cancer Genetics Group, University of Edinburgh, Scotland; Christopher Haiman, Sc.D., assistant professor, Keck School of Medicine, University of Southern California, Los Angeles; and Richard Houlston, M.D., Ph.D., professor, molecular and population genetics, Institute of Cancer Research, Sutton, U.K.; Durado Brooks, M.D., director, prostate and colorectal cancer, American Cancer Society, Atlanta; July 8, 2007, Nature Genetics; July 2007, Cancer Biology and Therapy


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