Ovarian Cancer Vaccine Might Extend Survival

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While phase I trials like this one are intended mainly to look at safety issues, they can often yield more information, Morgan said.

"While the classical goal of phase I trials is toxicity evaluation, these kinds of agents are different, because they usually don't have much in the area of toxicity," he explained. "What you're really looking for is a response to the proteins."

"I'm very encouraged," he continued.

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Fishman said the findings are promising, but even better vaccine candidates may lie ahead.

NY-ESO-1 "is probably not the best peptide to be used as a vaccine because all vaccines are based on targeting something unique to the disease, and this is not unique to ovarian cancer," Fishman said.

However, the study "does show the promise of immunotherapy," he added, "and as we become more sophisticated, hopefully someday we will be able to have vaccines that will treat or ultimately prevent one from developing cancer. That is the goal -- to vaccinate so you never get the disease."

More information

There's more on ovarian cancer at the U.S. National Cancer Institute.

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