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Second Gene That Increases MS Risk Found


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This could be just the beginning to unraveling the genetics of MS, experts said.

"What this tells us that now we have the technology to be able to identify genes that provide only a modest increase in the genetic risk of developing MS," Richert said. "We are going to figure out in relatively short order the genetic complements that set the inherited stage for developing MS."

"This is getting us into another pathway. It allows us to ask new questions, new relevant questions that we didn't know to ask before," Pericak-Vance said. "Now we have to figure how they're involved, if other genes in the pathway are involved."

Text Continues Below



But genetics are just part of the picture.

"We also have environmental influences as well," Gregory said. "Genetics will take us a certain distance, but there will be other environmental factors that contribute to developing MS."

More information

Visit the National Multiple Sclerosis Society for more on this disease.

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Copyright © 2007 ScoutNews, LLC. All rights reserved.
Last updated 7/30/2007

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SOURCES: Simon Gregory, Ph.D., assistant professor, medical genetics, Duke University, and molecular geneticist, Center for Human Genetics, Duke University, Durham, N.C.; Margaret Pericak-Vance, Ph.D., director, Miami Institute for Human Genomics, University of Miami Miller School of Medicine; John Richert, M.D., executive vice president, research and clinical programs, National Multiple Sclerosis Society, New York City; July 29, 2007, Nature Genetics


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