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Study Questions Genetic Screening for Treatable Diseases


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Zuckerman and his colleagues also questioned the use of genetic screening for other mild hereditary conditions.

"Applying the classic carrier screening paradigm to common, low-penetrance disease leads to inevitable dilemmas, and programs offering such screening should determine whether the true goal is knowledge and presymptomatic risk assessment or pregnancy termination of fetuses with a specified genetic status," the researchers wrote.

"Our results suggest that to avoid termination of pregnancies for generally mild conditions, even in a highly educated population, screening programs would require a combination of traditional, nondirective genetic counseling with medical counseling by professionals familiar with the specific diseases," they concluded.

Text Continues Below



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To learn more about Gaucher disease, visit the National Gaucher Foundation.

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-- Robert Preidt

Copyright © 2007 ScoutNews, LLC. All rights reserved.
Last updated 9/18/2007

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SOURCE: JAMA/Archives journals, news release, Sept. 17, 2007


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