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Study Reveals E.Coli's Grip on Gut


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The authors also found that individuals with HUS had an immune response to one component of HCP.

The research group is now looking to start experiments in animals and/or humans. "In our lab, we did in vitro experiments, but we are trying some collaboration with other universities to do some in vivo [in animals/humans] experiments," said Partha Samadder, a postdoctoral fellow in the lab of Jorge A. Giron, the study's lead author.

"Overall, it all has to be corroborated by others," Imperato said. "All that said, meaningful therapeutic interventions to prevent this cascade of molecular biological events will be years off. Meanwhile, the key is to prevent these infections in the first place."

Text Continues Below



There are ways to help prevent foodborne illness. They include:

  • Make sure ground beef and other meats as well as eggs are well cooked before you eat them.
  • Wash raw fruits and vegetables with soap. Pay particular attention to leafy greens as there are lots of crevasses and cracks where E. coli can hide.
  • Don't chop vegetables on the same block where you just made beef hamburgers or prepared other meat. Keep raw meat separate from ready-to-eat foods.
  • Keep raw and ready-to-eat foods completely separate.
  • Refrigerate leftovers promptly.
  • Avoid bruised produce such as tomatoes.
  • Make sure all cooking utensils including meat thermometers and cutting boards are thoroughly cleaned with soap and hot water after you've handled them.
  • Wash your hands regularly with soap and hot water.
  • Drink only pasteurized milk, juice or cider.
  • Drink municipal water that has been treated with chlorine or another disinfectant.

More information

There's more on E. coli at the U.S. Centers for Disease Control and Prevention.

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Copyright © 2007 ScoutNews, LLC. All rights reserved.
Last updated 10/18/2007

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SOURCES: Partha Samadder, Ph.D., postdoctoral fellow, department of immunobiology, University of Arizona, Tucson; Pascal James Imperato, M.D., distinguished service professor and chair, department of preventive medicine and community health, State University of New York Downstate Medical Center, New York City; Journal of Clinical Investigation


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