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Study Supports Controversial Heart Failure Drug


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Because of its small size and short follow-up, the Stanford study also failed to address the most important question of all: Does Natrecor increase patients' risk for death?

"Certainly this trial does not even attempt to answer mortality questions," Witteles agreed.

Those questions may only be answered by the large, prospective trial currently under development. "I think that that is the trial that will settle the matter," Sackner-Bernstein said. "That's the kind of trial I first asked for."

Text Continues Below



The results of that study will not arrive for at least four or five years, however. In the meantime, the debate over Natrecor continues.

More information

For more on heart failure, visit the American Heart Association.

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Copyright © 2007 ScoutNews, LLC. All rights reserved.
Last updated 10/29/2007

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SOURCES: Jonathan Sackner-Bernstein, M.D., associate chief of cardiology and director, Heart Failure Program, St. Luke's-Roosevelt Hospital Center, New York City; Ronald Witteles, M.D., instructor, cardiovascular medicine, Stanford University School of Medicine, Stanford, Calif; Oct. 30, 2007, Journal of the American College of Cardiology, online


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