New Worries Over Blockbuster Meds Avandia, Fosamax

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Again, the authors cautioned, risks and benefits should be carefully weighed when prescribing the drug.

Other studies have also reported atrial fibrillation as a side effect of bisphosphonates, the class of drugs that includes Fosamax.

Ronald Rogers, a spokesman for Fosamax manufacturer Merck & Co. Inc., called the Fosamax-fibrillation association an "old issue." He also pointed to an article published earlier this year in the British Medical Journal that found no such association.

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Rogers also pointed out that the current study is an observational one and therefore subject to limitations not seen in a previous randomized trial. That trial saw an increase in the incidence of "serious" atrial fibrillation among Fosamax patients, he said, but it did not reach a statistically significant difference.

More information

There's more on type 2 diabetes at the American Diabetes Association.

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