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Bacterial Infection May Boost SIDS Risk


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As an accompanying editorial pointed out, the number of SIDS cases peaks at 8 weeks to 10 weeks of age. That's a time-frame coinciding with blood concentrations of immunoglobulin that protect newborns against bacterial infections.

"This is just at the point that antibodies that go across the placenta -- from mom to baby -- to protect them are starting to disappear, and babies haven't made a lot of their own antibodies yet," noted Dr. Cheryl Cipriani, an associate professor of pediatrics at Texas A&M Health Science Center College of Medicine and a neonatologist with Scott & White. "This is a particular point in time where babies seem to be vulnerable," she said.

Also, both S. aureus and E. coli are bacteria that make toxins, Cipriani explained, "and a toxin might not necessarily cause all the histological changes that you see with infections."

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"This is another building block in our knowledge about these kinds of deaths, but association doesn't mean cause," Cipriani cautioned. "But it's a large enough group of babies where you think the findings need to be paid attention to."

There was other news on the underlying causes of SIDS. Reporting in the June 1 issue of the American Journal of Respiratory and Critical Care Medicine, Canadian researchers say that over-wrapping baby, or keeping the room temperature too high, might lead to overheating, which in turn appears to raise SIDS risk.

The team, led by pediatrician Dr. Shabih Hassan of the University of Calgary, Alberta, also found that mothers who smoke while pregnant also boost their baby's odds for SIDS.

Until precise causes for SIDS are uncovered, parents should be aware that putting infants to sleep on their back ("Back to Sleep") reduces the risk of SIDS by 40 percent to 60 percent, Greenberg noted. Avoiding your child's exposure to cigarette smoke also reduces this risk.

Using a pacifier might also lower risk, but this is controversial, Greenberg added.

More information

There's more on SIDS at the National Institute of Child Health and Human Development.

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Copyright © 2008 ScoutNews, LLC. All rights reserved.
Last updated 5/30/2008

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SOURCES: Nigel Klein, MBBS, Ph.D., professor of infectious disease and immunology, and head, department of infection, University of London and Great Ormond Street Hospital for Children, London, U.K.; Jim Greenberg, M.D., director, division of neonatology, Cincinnati Children's Hospital; Cheryl Cipriani, M.D., associate professor of pediatrics, Texas A&M Health Science Center College of Medicine, and neonatologist, Scott & White, Temple, Texas; May 30, 2008, press release, University of Calgary; May 31, 2008, The Lancet


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