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According to the study authors, a low-carbohydrate, non-restricted-calorie diet may be optimal for those who will not follow a restricted-calorie dietary regimen. The increasing improvement in levels of some biomarkers up to the 24-month point, despite the achievement of maximum weight loss by six months, suggests that a diet with a healthful composition has benefits beyond weight reduction.

"The three diet strategies were beneficial for two years for all the biomarkers, but some of them were more specifically better than others," Shai said. "The good news is that you can consider and choose one strategy, but, once you choose one, you should stick with it."

"You have to look at each individual," added Lisa Harper Mallonee, a registered dietitian and an assistant professor of dental hygiene at the Texas A&M Health Science Center Baylor College of Dentistry. "Practice moderation and creating individual, healthy diets."

Text Continues Below



More information

The American Heart Association has more on the Mediterranean diet.

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Last updated 7/16/2008

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SOURCES: Iris Shai, R.D., Ph.D., researcher, department of epidemiology, Ben-Gurion University of the Negev, Beer-Sheva, Israel; Lisa Harper Mallonee, R.D./L.D., assistant professor, dental hygiene, Texas A&M Health Science Center Baylor College of Dentistry; July 17, 2008, New England Journal of Medicine


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