Possible Cause of Postpartum Depression Pinpointed

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"We don't know if this is the same mechanism in humans, but I think all indications are there," Mody said. "The women that are affected by the disorder, the hormone levels are not changed, they are not different than in unaffected women. So, we are confident that it must be the receptor trafficking mechanism that is affected, because the changes in hormone levels are pretty normal."

Dr. Julio Licinio, chairman of the department of psychiatry and behavioral sciences at the University of Miami Miller School of Medicine, praised the research as "very interesting," particularly its development of a new animal model of postpartum depression, which can aid both research and drug development.

"This is probably the strongest [animal] model I have seen in a long time," he said.

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More information

For more on postpartum depression, visit womenshealth.gov.

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