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Genetic Trait Linked to Alcoholism



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"We know that serotonin is critical to maintaining a positive sense of self and for controlling our anxiety," Philibert said. That could explain a possible connection between serotonin levels and alcoholism, he added.

Li cautioned, however, that it's unlikely that a single genetic trait by itself would make someone more susceptible to alcoholism. It's more likely that a genetic variation works with other genes to raise the risk, he said.

Philibert said research might lead to a day when doctors could look at an alcoholic's genetic traits and discover whether antidepressants could help that person.

Text Continues Below



Doctors, he said, might say, "You have this genotype and you drink a lot, so you may benefit from a drug like Prozac."

More information

Learn more about alcoholism from the U.S. National Institute on Alcohol Abuse and Alcoholism.

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Copyright © 2008 ScoutNews, LLC. All rights reserved.
Last updated 11/20/2008

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SOURCES: Ming D. Li, Ph.D., professor and head of neurobiology, University of Virginia, Charlottesville; Robert Philibert, M.D., Ph.D., director of the Laboratory of Psychiatric Genetics, University of Iowa, Iowa City; February 2009, Alcoholism: Clinical & Experimental Research


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