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Page: << Prev | 1 | 2 "Mice lacking SIRT6 seem to hit some kind of a wall at around 4 weeks of age when their blood sugar drops to a level barely compatible with life," Dr. Katrin Chua, assistant professor of endocrinology, gerontology and metabolism at Stanford, said in the news release. "Reducing NF-kB activity somehow allows the mice to get over this critical period and to live much longer."
Trying to figure out how NF-kB knows the timing and extent of its role in aging and how SIRT6 might affect this is the next step for the researchers.
"It's a very provocative question," Chang said. "We've tied together two previously separate pathways in aging. Now we'd like to better understand what regulates that pathway."
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The U.S. Centers for Disease Control and Prevention has more about healthy aging.
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-- Kevin McKeever
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