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Parental Distrust May Explain Lack of Black Children in Clinical Trials


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The researchers said that the "distrust may be attributed both to a cultural memory of victimization and exploitation during clinical experiments, such as in the Tuskegee Syphilis Study, and to personal experiences with discrimination."

The government-sponsored Tuskegee Study, named after a town in Alabama where participants were recruited, included several hundred poor, black sharecroppers, some of whom had syphilis. Researchers failed to inform the infected men of their diagnosis, telling them instead that they had "bad blood," which could mean anemia or even fatigue. Lifesaving drugs were purposely withheld so the "natural" course of the disease could be observed. The experiment was shut down after a leak to the press in 1972.

According to the experts, strategies that may help overcome the distrust of blacks toward medical research include culturally appropriate recruitment materials, use of research assistants with similar racial and cultural backgrounds, and the establishment of community research advisory boards.

Text Continues Below



More information

The U.S. Food and Drug Administration has more about children and clinical trials.

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-- Robert Preidt

Copyright © 2009 ScoutNews, LLC. All rights reserved.
Last updated 2/6/2009

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SOURCE: JAMA/Archives journals, news release, Feb. 2, 2009


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