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Gene Test Could Predict Thyroid Cancer Risk
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Page: << Prev | 1 | 2 | 3 However, Dr. Len Lichtenfeld, deputy chief medical officer of the American Cancer Society, doesn't think that these mutations could be used to predict the risk of thyroid cancer.
"They have demonstrated that there is a relationship between these genes and thyroid cancer," Lichtenfeld said. "But that relationship is not what I would call an absolute relationship, because these mutations were also in a significant percentage of the control patients as well."
One of the mutations was present in 35 percent of the population, and the other mutation was present in more than 50 percent of the population, Lichtenfeld noted. "Yes, these mutations occur with a higher frequency in patients with thyroid cancer compared to controls -- the reality is, they also appear in a fair number of control populations," he said.
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These mutations are not discriminating enough to tell who is really at a higher risk of developing thyroid cancer, Lichtenfeld noted.
More information
For more on thyroid cancer, visit the American Cancer Society.
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Last updated 2/6/2009
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SOURCES: Kari Stefansson, M.D., CEO, deCODE Genetics, Reykjavik, Iceland; Scott Rivkees, M.D., director, Yale Pediatric Thyroid Center, Yale University, New Haven, Conn.; Len Lichtenfeld, M.D., deputy chief medical officer, American Cancer Society, Atlanta; Feb. 6, 2009, Nature Genetics, online
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