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Studies Report More Harmful Effects From BPA


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Women are more likely to die after a heart attack than men, and Belcher suspects an increased rate of arrhythmia might bear some of the responsibility for that trend.

His team is currently collecting human heart cells from transplant patients to try to replicate the findings.

In another study, researchers report on the mechanism by which BPA affects fertility in the offspring of rodents.

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"The genes that are necessary for normal pregnancy are altered," explained study author Dr. Hugh Taylor, director of the division of reproductive endocrinology at Yale University School of Medicine. "It changes the DNA code and the ability of DNA to express these genes."

"A little transient exposure during a brief time period in pregnancy could permanently alter the DNA of the uterus," Taylor added.

For pregnant women, the message is "just try avoiding drinking out of hard water bottles and eating out of cans and perhaps not getting expensive dental work with sealants," Taylor said. "There's nothing wrong with eating fresh vegetables."

In a third study, researchers warned that people may be getting higher-than-recommended exposure to BPA from both known and unknown sources, a conclusion they drew from research involving monkeys. The researchers, from the University of Missouri, had compared the blood level of BPA in monkeys given high doses of the chemical with average levels found in people in the United States and other developed countries.

More than 8 billion pounds of BPA are used in the manufacturing of products each year, they said.

Chemical industry representatives, however, disagree that the findings represent any real threat to human health.

"It is disappointing to see that researchers continue to inject animals with bisphenol A since studies of this type have recently been acknowledged by the National Institute of Environmental Health Sciences to have limited impact on our ability to assess human health effects," said Steve Hentges, executive director of the Polycarbonate/BPA Global Group at the American Chemistry Council.

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Copyright © 2009 ScoutNews, LLC. All rights reserved.
Last updated 6/10/2009

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SOURCES: Hugh Taylor, M.D., associate professor, and director, division of reproductive endocrinology, Yale University School of Medicine, New Haven, Conn.; Scott Belcher, Ph.D., associate professor, pharmacology, University of Cincinnati; Steven G. Hentges, Ph.D., executive director, Polycarbonate/BPA Global Group, American Chemistry Council, Arlington, Va.; June 10, 2009, presentations, Endocrine Society annual meeting, Washington, D.C.


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