Statins May Cause Muscle Damage in Some Patients

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"It's a very interesting study," said Blumenthal, director of the Johns Hopkins Ciccarone Preventive Cardiology Center in Baltimore. "This whole issue of why about one in 50 people on statins gets recurrent or severe muscle pain is very frustrating for physicians."

Known risk factors for muscle pain include old age, high doses of statins, exercising vigorously while on statins and certain medications, including warfarin (Coumadin), cancer drugs, oral medications for fungal disorders and certain antibiotics, which interfere with the removal of statins from the body.

In 2001, cerivastatin (Baycol) was withdrawn from the market because of a high incidence in rhabdomyolysis, a widespread breakdown of skeletal muscle tissue.

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Learn more about statins from the U.S. National Library of Medicine.

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