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Even Mild Infections Hasten Decline With Alzheimer's
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Page: << Prev | 1 | 2 | 3 "This study raises the question of whether or not anti-inflammatory drugs in previous and perhaps future trials may have been or may be more helpful in the subset of dementia patients with other conditions causing inflammation outside the brain," he said. "If this is true, it might help explain why people taking anti-inflammatory drugs for systemic inflammatory diseases appear to have less risk for getting Alzheimer's."
Maria Carrillo, director of medical and scientific relations at the Alzheimer's Association, noted that TNF-a is not the only protein involved in inflammation and cognition.
"This study tells us that inflammatory processes are involved in cognition," Carrillo said. "TNF-a could be a therapeutic target, but there are other neuromodulators out there that are therapeutic targets," she said.
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More information
For more information on Alzheimer's disease, visit the Alzheimer's Association.
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Copyright © 2009 ScoutNews, LLC. All rights reserved.
Last updated 9/8/2009
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SOURCES: Clive Holmes, MRCPsych, Ph.D., Clinical Neurosciences Research Division, University of Southampton, U.K.; Greg M. Cole, Ph.D., neuroscientist, Greater Los Angeles VA Healthcare System, and associate director, Alzheimer's Disease Research Center, UCLA David Geffen School of Medicine; Maria Carrillo, Ph.D., director, medical and scientific relations, Alzheimer's Association; Sept. 8, 2009, Neurology
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