Scientists Find Clue to Dangerous Side Effect of MS Drug

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Two other papers in the same issue of the journal described case studies of patients with multiple sclerosis who developed PML after using Tysabri. One was a 52-year-old man who became critically ill but eventually recovered.

The second was a 35-year-old man, who also recovered. The authors of this paper stressed that the risk of PML in patients being treated with Tysabri is still low, about one in 1,000 and possibly even lower.

Until there is a good way to predict who is at risk for PML, experts urged doctors to be alert for early signs of this brain infection.

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"Patients and physicians still need to have tight vigilance for any new symptoms that can occur while a patient is on Tysabri," O'Looney said.

More information

The National Multiple Sclerosis Society has more on living with MS.

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