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Successful Dieters Show Unique Brain Patterns

Scans found regions related to inhibition, self-control were more active

By Randy Dotinga
HealthDay Reporter


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WEDNESDAY, Sept. 23 (HealthDay News) -- New research suggests that people who have successfully lost weight will activate certain parts of their brains when confronted with images of food.

While preliminary, the findings indicate that those who shed pounds -- and keep them off -- tap into regions of the brain related to control over urges.

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"It may be that they actually recruit new brain regions to help with their weight loss," said study author Jeanne McCaffery, an assistant professor of psychiatry and human behavior at Brown Medical School, in Providence, R.I.

McCaffery and her colleagues wanted to understand how people react to "food cues" -- in this case, photos of food. "People make decisions about whether or not they're going to eat food, and that decision-making usually comes when they first smell or see the food," she said.

The researchers recruited several groups of participants: 18 people of normal weight, 16 fat people and 17 people who had successfully shed weight -- at least 30 pounds from their maximum weight -- and kept it off for at least three years.

The participants underwent brain scans as they looked at pictures of high-calorie and low-calorie foods. The MRI scans revealed that those who had successfully lost weight showed more activity in the parts of the brain that are associated with inhibition and in dealing with complex tasks, McCaffery said.

Those of normal weight didn't show this pattern. This may be because "they've been of normal weight all of their lifetime. The successful weight losers have to put in more effort to avoid eating foods or to control their response to food."

The findings appear in the October issue of the American Journal of Clinical Nutrition.

Ian McDonald, a professor of metabolic physiology who wrote a commentary accompanying the study, said questions remain.

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Copyright © 2009 ScoutNews, LLC. All rights reserved.
Last updated 9/23/2009

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SOURCES: Jeanne McCaffery, Ph.D., assistant professor, psychiatry and human behavior, Weight Control and Diabetes Research Center, Brown Medical School and The Miriam Hospital, Providence, R.I.; Ian McDonald, researcher, School of Biomedical Sciences, University of Nottingham Medical School, Queen's Medical Centre, Nottingham, United Kingdom; October 2009, American Journal of Clinical Nutrition


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