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Red-Grape Compound May Improve Diabetes
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Page: << Prev | 1 | 2 The insulin levels in the other mice went up, apparently because of their diets.
So why not drink red wine to get the same effects? It won't work, Coppari said, since the amount of resveratrol in red wine is too low. Then there's the matter of the barrier between the bloodstream and the brain, which keeps things out of the brain.
"Clearly, administration of drugs to patients directly into the brain for chronic diseases is not feasible or realistic," said Lindsay Brown, of the University of Queensland's department of physiology and pharmacology in Australia.
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"But this study may lead to the development of compounds that are more effective in crossing from the blood to the brain than is resveratrol," said Brown.
The study, which was supported by the American Heart Association, National Institutes of Health and American Diabetes Association, was published online in advance of its print publication in the December issue of the journal Endocrinology.
More information
Learn more about resveratrol from Oregon State University.
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Copyright © 2009 ScoutNews, LLC. All rights reserved.
Last updated 10/22/2009
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SOURCES: Roberto Coppari, Ph.D., assistant professor, internal medicine, University of Texas Southwestern Medical Center, Dallas; Lindsay Brown, Ph.D., University of Queensland's department of physiology and pharmacology, Australia; December 2009 Endocrinology
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