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Mental 'Exercise' May Only Hide Signs of Alzheimer's

Games, reading help mask trouble in brain, study suggests, making later progress of disease seem quicker

By Melissa Lee Phillips
HealthDay Reporter


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WEDNESDAY, Sept. 1 (HealthDay News) -- Reading, crossword puzzles and other mentally stimulating activities have pros and cons when it comes to Alzheimer's disease, new research suggests.

In line with prior research, the study finds that such mental activity may slow declines in thinking and memory during normal old age.

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But folks who loved these pursuits actually displayed a hastening of their mental decline once symptoms of dementia began to set in, the researchers say.

"We think there's a trade-off," said senior study author Robert Wilson of Rush University Medical Center in Chicago. Keeping mentally active means that there is "a little more time during which the person is cognitively competent and independent and a little less time in a disabled and dependent state" once dementia does set in, said Wilson, who is senior neuropsychologist at Rush's Alzheimer's Disease Center.

The findings were published online Sept. 1 in Neurology.

Previous work has suggested that engaging in cognitively challenging activities may help ward off the appearance of dementia in older people. To test this, Wilson and his co-workers tracked almost 1,200 older individuals over nearly 12 years.

The team assessed each person's engagement in mentally stimulating pursuits using a 5-point "cogntive activity" scale.

At the time of study enrollment, all of the participants were free of dementia; by the study's end, 614 people were cognitively normal, 395 showed mild cognitive impairment, and 148 had Alzheimer's disease.

The researchers found that increased cognitive activity among normal individuals -- things such as listening to the radio, watching television, reading, playing games and going to museums -- meant that they were less likely to experience cognitive decline over several years.

Specifically, for each gained point on the cognitive activity scale, the rate of mental decline fell by 52 percent over 6 years.

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Copyright © 2010 HealthDay. All rights reserved.
Last updated 9/1/2010

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SOURCES: Robert S. Wilson, Ph.D., senior neuropsychologist, Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois; Charles B. Hall, Ph.D., professor of neurology, Albert Einstein College of Medicine, New York City; Sept. 14, 2010 , Neurology


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