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(Ivanhoe Newswire) -- You may want to start adding more tofu, veggie burgers or other soy foods to your plate. New evidence suggests an antioxidant found in soybeans may prevent the spread of prostate cancer.
Researchers at Northwestern University in Evanston, Ill. say genistein, a compound found in soybeans, almost completely prevented the spread of human prostate cancer in mice. Metastasis of prostate cancer to the lungs reduced by 96 percent when mice were given the amount of genistein comparable to what a human would eat in a soybean-rich diet.
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Researchers say it is not clear how genistein stops the spread of prostate cancer -- genistein did not reduce the size of tumors. An earlier study of prostate cell cultures found genistein prevents cells from detaching from tumors, which may prevent cancer from migrating to other parts of the body. These impressive results give us hope that genistein might show some effect in preventing the spread of prostate cancer in patients, Raymond C. Bergan, M.D., the studys senior investigator and director of experimental therapeutics for the Robert H. Lurie Comprehensive Cancer Center of Northwestern University, was quoted as saying. Certain chemicals have beneficial effects and now we have all the preclinical studies we need to suggest genistein might be a very promising chemopreventive drug.
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SOURCE: Cancer Research, 2008;68:2024-2032
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