Experts Release New Cystic Fibrosis Guidelines

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The guidelines recommend against:

• Systemic corticosteroids in children because of "an excess number of adverse events," including abnormalities in glucose metabolism, cataracts, and percentage of patients "colonized" with Pseudomonas. This recommendation excludes patients with concomitant asthma.
• Inhaled corticosteroids, because there's no clinical benefit. This recommendation excludes patients who also have asthma, however.
• Prophylactic anti-Staphylococcal antibiotics because of the lack of clinical efficacy and an apparent increase in P. aeruginosa infections with their use.

There wasn't sufficient evidence to recommend for or against other types of treatment, said Flume and his colleagues.

The guidelines are published in the second issue for November of the American Journal of Respiratory and Critical Care Medicine.

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More information

The March of Dimes has more about cystic fibrosis.

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-- Robert Preidt