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Surprise in Lab Helps ID Drug to Fight ALS


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The discovery of the interaction between SOD1 and Rac1 may prove to have widespread importance.

"It is exciting not only from the standpoint of ALS, but also because of its implications for understanding basic cell biology. Rac1 is implicated in many cellular processes including cellular migration, proliferation and differentiation, and is an important component of inflammatory disease processes," team leader John Engelhardt, head of anatomy and cell biology at UI's Roy J. and Lucille A. Carver College of Medicine, said in a prepared statement.

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The Muscular Dystrophy Association has more about ALS.

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-- Robert Preidt

Copyright © 2008 ScoutNews, LLC. All rights reserved.
Last updated 1/24/2008

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SOURCE: University of Iowa, news release, Jan. 24, 2008


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