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Hunger Hormone Makes Food Look More Tasty


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"So, I don't really buy that the parallel," added Kahn. "There may be aspects of overeating that may be related to aspects of addiction. But overeating is not just another addiction."

In the same journal, a separate animal study out of Duke University Medical Center highlights a potentially new way to help people curb their appetites and achieve weight control.

Study researchers report that by blocking activation of a key brain enzyme (CaMKK2), they were able to short-circuit the normal flow of the ghrelin pathway in mice, preventing the activation of a second enzyme (AMPK) that directly triggers the desire to eat. The finding, they said, appears to open up a fresh target for drugs geared at reducing appetite.

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For additional information on weight management, visit the National Institute of Diabetes and Digestive and Kidney Diseases.

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Last updated 5/7/2008

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SOURCES: Alain Dagher, M.D., associate professor, Montreal Neurological Institute of McGill University, Montreal; Barbara B. Kahn, M.D., chief, division of endocrinology, diabetes and metabolism, Beth Israel Deaconess Medical Center, and professor, medicine, Harvard Medical School, Boston; May 2008, Cell Metabolism


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