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Antidepressants May Prevent Depression After Stroke


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"We need more research on treatment of post-stroke depression," Smith said. "Whether it's better to try to prevent depression, rather than treating depression after it develops, is not certain at this point," he added.

In this study, the majority of untreated patients (78 percent) never developed depression, Smith noted. "I'm not sure that my patients would want to take a brain chemical-altering drug based on a less than 50 percent chance of developing depression," he said.

"For now, I think it's most important that patients be evaluated by physical, occupational and speech therapy, as needed," Smith said. "The appropriate therapies for that individual, taking into account both the patient's individual needs and the institutional resources, can then be initiated."

Text Continues Below



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For more information on stroke, visit the American Stroke Association.

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Copyright © 2008 ScoutNews, LLC. All rights reserved.
Last updated 5/27/2008

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SOURCES: Larry B. Goldstein, M.D., professor, neurology, and director, Duke Center for Cerebrovascular Disease, Duke University Medical Center, Durham, N.C.; Argye Hillis, M.D., associate professor, neurology, Johns Hopkins University, Baltimore; Eric Smith, M.D., M.P.H., assistant professor, neurology, and associate director, Acute Stroke Services, Massachusetts General Hospital and Harvard Medical School, Boston; May 28, 2008, Journal of the American Medical Association


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