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Green Tea Antioxidant May Help Prevent Alzheimer's
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Page: << Prev | 1 | 2 | 3 In related research, a team of American scientists said that interrupting a key signaling pathway in immune system cells allowed those cells to enter the brain and attack and remove amyloid plaque.
Reporting May 30 in Nature Medicine, a team led by research scientist Terrence Town, of Cedars-Sinai Medical Center, Los Angeles, conducted their study in genetically engineered mice. The group blocked a molecule that typically suppresses a portion of the immune response. Once the system was freed up, immune cells called macrophages made their way to the brains and devoured up to 90 percent of amyloid plaques, the team said.
"If these experimental animals are representative of the clinical syndrome of Alzheimer's disease, we may have a therapeutic target that we did not have before," study co-author Dr. Jun Tan, of the University of South Florida, said in a statement.
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For more about Alzheimer's disease, visit the Alzheimer's Association.
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Copyright © 2008 ScoutNews, LLC. All rights reserved.
Last updated 5/30/2008
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SOURCES: Erich Wanker, Ph.D., Max Delbrueck Center for Molecular Medicine, Berlin, Germany; Greg M. Cole, Ph.D., neuroscientist, Greater Los Angeles VA Healthcare System, and associate director, Alzheimer's Disease Research Center, UCLA David Geffen School of Medicine; May 30, 2008, online edition, Nature Structural & Molecular Biology; May 30, 2008, statement, Cedars-Sinai Medical Center, Los Angeles
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