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Chinese Red Yeast Rice May Prevent Heart Attack


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Capuzzi said a drug that includes Chinese red yeast rice may soon be used much the same way as cholesterol-lowering drugs to prevent heart attacks.

One heart expert thinks this study shows that Chinese red yeast rice may be another way to lower cholesterol, thereby preventing heart attack.

"Numerous clinical trials have established that statin medications in conjunction with lifestyle modification reduce the risk of recurrent cardiovascular events and prolong life in patients with prior myocardial infarction [heart attack] and elevated, average, or below average cholesterol levels," said Dr. Gregg C. Fonarow, director of the Ahmanson-UCLA Cardiomyopathy Center at the University of California, Los Angeles.

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This new study may extend these prior findings to the statin medication lovastatin, which is derived from Chinese red yeast, Fonarow said.

"However, it is very important to note, as the authors do in the paper, that the various components of the specific XZK preparation used in this trial have not been adequately studied for its consistency, stability, and individual pharmacologic properties. As such, further study is required," Fonarow said.

Another expert thinks that red yeast rice might confer an extra measure of protection against heart attack.

The extract of red yeast rice contains lovastatin, a drug that has been proven to improve cholesterol profiles and decrease risk of heart attack, said Dr. Byron Lee, an associate professor of cardiology at the University of California, San Francisco.

"However, the improvement in the patients on the extract is far beyond what you would expect with lovastatin alone, so maybe there is some other natural component in the extract that is conferring the extra benefit," Lee said. "That would be quite exciting."

Chinese red yeast rice is rice that has been fermented by red yeast. This rice has been used in China for many centuries as a food preservative, food coloring, spice, and in rice wine. Red yeast rice remains a staple in China, Japan and in Asian communities in the United States.

Red yeast rice also has been used as a medicine for more than 1,000 years. It has been used to improve blood circulation and treat indigestion and diarrhea, the study authors said.

More information

For more on Chinese red yeast rice, visit the U.S. National Library of Medicine.

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Copyright © 2008 ScoutNews, LLC. All rights reserved.
Last updated 6/13/2008

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SOURCES: David M. Capuzzi, M.D., Ph.D., director, Cardiovascular Disease Prevention Program, Myrna Brind Center of Integrative Medicine, Thomas Jefferson University, Philadelphia; Gregg C. Fonarow, M.D., director, Ahmanson-UCLA Cardiomyopathy Center, University of California, Los Angeles; Byron Lee, M.D., associate professor, cardiology, University of California, San Francisco; June 15, 2008, American Journal of Cardiology


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