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Free Drug Samples May End Up Costing More


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Midway through the study period, the institution's so-called "drug sample closet" was closed due to a physical relocation of the facility -- meaning that for the next nine months, doctors were unable to distribute the free brand name drug samples that had been previously available.

Using a pharmacy database, Miller and his colleagues characterized the nearly 2,000 chronic prescriptions for blood pressure, diabetes, ulcers, and gastrointestinal problems that were issued during the first nine months, while drug samples were still available. They then compared those patterns with prescriptions issued by the same doctors over the next nine months.

According to the researchers, the overall percentage of money-saving generic drugs prescribed to uninsured patients more than doubled once samples became unavailable -- from 12 percent while supplies lasted to 30 percent when the flow of free samples dried up.

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This dynamic, however, did not appear to be in play for Medicaid patients, who were typically prescribed generic drugs regardless of sample availability. According to the researchers, that might stem from the fact that doctors know that Medicaid patients typically incur the same minimal out-of-pocket expense for generic or brand name drugs, so there was less incentive to try and save the patient money with a free sample.

But for the uninsured, it's a different story. "Physicians assume they are helping out by giving a free sample to patients who have no insurance," Miller said. "But there are, nevertheless, unintended consequences to that action that physicians need to weigh when doing so."

A representative of the pharmaceutical industry took issue with the findings.

In a statement, Ken Johnson, senior vice president of the Pharmaceutical Research and Manufacturers of America (PhRMA), said the study, "overlooks the fact that Americas physicians prescribe medicines based on a wide range of factors, not simply receipt of samples." He added that, "free samples provide physicians valuable first-hand experience with new medicines. In many cases, samples help patients begin treatment sooner by quickly discovering the medicines that are best for them. And they can be an important option for patients in need of help."

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Copyright © 2008 ScoutNews, LLC. All rights reserved.
Last updated 9/5/2008

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SOURCES: David P. Miller, M.D., internal medicine physician, Wake Forest University Baptist Medical Center, Winston-Salem, N.C.; Reginald Frye, Ph.D., Pharm.D., associate professor, department of pharmacy practice, University of Florida College of Pharmacy, Gainesville; Sept. 5, 2008, news release, Pharmaceutical Research and Manufacturers of America; September 2008, Southern Medical Journal


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