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Ovarian Cancer Breakthrough Heralds New Era of Treatment


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The research team further validated the findings by examining additional tumor samples from across Canada and around the world.

In the past, analyzing the sequence of a tumor was a laborious process, and most studies could only look at one or only a few of the 20,000 genes in the human genome. The new sequencing technologies allow scientists to look at all at once.

"This task would have been unfathomable in terms of both cost and complexity even two years ago," said Dr. Marco Marra, director of the BC Cancer Agency's Genome Sciences Center.

Text Continues Below



Researchers chose granulosa cell tumors because, unlike other cancers, they are "clinically homogenous," Huntsman said.

"This cancer is unique," said Dr. Dianne Miller, a gynecologic oncologist at BC Cancer Agency and Vancouver General Hospital. "For patients with this tumor type, it means they should all have the same response to the same treatment. And now that we have this pathway, we can look for existing cancer drugs that might work on this particular gene mutation to make the cancer disappear."

Researchers plan to study other rare tumor types using a similar method.

More information

The American Cancer Society has more on ovarian cancer.

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-- Jennifer Thomas

Copyright © 2009 ScoutNews, LLC. All rights reserved.
Last updated 6/10/2009

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SOURCE: University of British Columbia, news release, June 10, 2009


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