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New Treatments to Chase Away Wrinkles, Frowns
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Page: << Prev | 1 | 2 | 3 | Next >> Two that could receive FDA approval this fall are composed of hyaluronic acid, a naturally occurring component of connective tissue. One, a synthetically manufactured product available in two forms, called Restylane and Perlane, promises effects that last up to a year, said New York City plastic surgeon Dr. Z. Paul Lorenc. Restylane is for fine lines, and Perlane is for deeper skin folds.
In a study of 134 people comparing Restylane with a popular form of collagen called Zyplast, Lorenc found that after six months 57 percent of the participants preferred Restylane, 33 percent thought both products performed equally well, and 9.5 percent preferred Zyplast.
The other hyaluronic acid-based product about to be reviewed by the FDA is called Hylaform. It is extracted from rooster combs, and lasts for between three and six months, according to the ASPS.
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Another new product is called Artefill. It has received preliminary FDA approval, and is sold under the brand name Artecoll in Europe. It is billed as a permanent way to assure smooth skin by injecting a combination of collagen and non-silicone polymers at wrinkle sites.
These so-called "microspheres" don't get absorbed into the body. Rather, the body forms collagen around them, according to Dr. Gottfried Lemperle, a plastic surgeon at the University of California, San Diego. He is a consultant to and shareholder of Artes Medical Inc., of San Diego, which manufactures Artefill.
"We inject plastic spheres that act as a scaffold for the body's own collagen, and the spheres stay in place held by the patient's own tissue," he said.
The downside is the chance that patients will get nodules -- hard bumps -- around their lips, which then must be treated, Lemperle said. Also, there have been some reports that the spheres moved from the injection site, and also caused redness. Lemperle claimed these side effects weren't due to the product itself, but because the doctors performing the procedures were not properly trained in its use.
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Copyright © 2003 ScoutNews, LLC. All rights reserved.
Last updated 9/19/2003
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SOURCES: James Wells, M.D., president, American Society of Plastic Surgeons, Arlington Heights, Ill.; Caroline Glicksman, M.D., plastic surgeon, Sea Girt, N.J.; Miles Graivier, M.D. plastic surgeon, Roswell, Ga.; Gottfried Lemperle, M.D., Ph.D., clinical professor, Division of Plastic Surgery, University of California, San Diego;
Z. Paul Zorenc, M.D., plastic surgeon, assistant professor of plastic surgery, New York University School of Post Graduate Medicine, New York City; Sept. 17, 2003, meeting of the American Society of Plastic Surgeons, New York City
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