For Some, Long Life Is in the Genes

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Barzilai, for one, would take it. He has a family history of high cholesterol and is currently taking two drugs and exercising to stay healthy. His cholesterol levels are fine, but the size of his particles are small. Meanwhile, Pfizer is in the advanced stage of trials for a drug that would increase the size of HDL particles. "I'll certainly take that instead of the other drugs and measure the size," he says.

His aim, he says, is not necessarily to live longer but to live healthier. "What I'm after is better health," Barzilai says. "It happens that the mechanisms that I'm looking at will also extend life span and I apologize for that, but that's the way I tackled this problem."

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For more on healthy aging, visit the National Institute on Aging (www.nia.nih.gov) or the National Council on the Aging (www.ncoa.org).

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