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Short-Term Celebrex Safe Against Cirrhosis


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The data, Friedman added, is not really all that surprising since prior animal studies had indicated that the kidney problems associated with NSAIDs were attributable to the blockage of the cox-1 enzyme rather than the cox-2 enzyme.

Traditional NSAIDs such as naproxen block both enzymes, while the cox-2 inhibitors, as their name suggests, block only the cox-2 variant.

More information

Text Continues Below



The National Institutes of Health (digestive.niddk.nih.gov ) has more on cirrhosis of the liver.

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Copyright © 2005 ScoutNews, LLC. All rights reserved.
Last updated 2/23/2005

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SOURCES: Scott Friedman, M.D., Fishberg professor of medicine, and chief, division of liver disease, Mount Sinai School of Medicine, New York City; March 2005 Hepatology


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