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They also discovered that being the first-born in a family meant a lot, boosting the odds of making it to 100 by nearly 80 percent.

"But nobody knew why that was -- sometimes in research you get answers, but you also get new questions," Gavrilov said.

So, he and his wife set out to solve that puzzle. They selected 198 centenarians from across the United States, checking and double-checking their ages using every form of documentation available. Comparing the centenarians' histories to those of their siblings, the researchers then analyzed the data to help explain the "first-born effect."

Text Continues Below



One theory -- that first-born children might have been relatively protected from pediatric illness because they weren't surrounded by disease-bearing siblings in infancy -- didn't pan out. "We found that even at age 75 it still matters that one is first-born," Gavrilov said. "It's a late-life phenomenon."

A second theory -- that first-born kids reaped the benefit of a relatively young, strong and productive father -- also fell flat. "We got the very clear result that the father's age wasn't important," the Chicago researcher said.

That wasn't the case for mothers. In fact, statistical analysis revealed that young maternal age at birth completely accounted for the first-born effect.

"It is very rare in science that you have such clear-cut results. But here, when we saw the results, we went 'Wow,'" Gavrilov said. Overall, children born to an under-25 mother had double the odds of living to 100 and beyond, compared to offspring of women who delivered at a later age.

So, why do young moms tend to bear more long-lived children? "At this point all we have is hypotheses," Gavrilov said. "One is biological -- that maybe the eggs are different in their quality, and the best ones, the most vigorous eggs, go first to fertilization."

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Copyright © 2006 ScoutNews, LLC. All rights reserved.
Last updated 4/17/2006

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SOURCES: Leonid Gavrilov, Ph.D., Center on Aging, University of Chicago; Georgeanne Patmios, O.D., acting chief, Population and Social Processes Branch of the Behavioral and Social Research Program, U.S. National Institute on Aging, Bethesda, Md.; March 30-April 1, 2006, presentation, Population Association of America annual meeting, Los Angeles


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