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Scientists ID Brain Pathway That Stops Seizures


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"One of the most exciting aspects of the work is that it highlights the potent anti-epileptic effects of acid in the brain -- effects that have been recognized for nearly 100 years but until recently have been poorly understood -- and it identifies ASIC1a as a key player in mediating the anti-epileptic effect of low pH," Ziemann said.

Seizures occur when brain neurons work out of synch, causing physical spasms or convulsions and even disrupting vital functions, such as breathing. Most seizures stop by themselves, but if they don't, a life-threatening condition called status epilepticus that claims a mortality rate of up to 20 percent could occur.

It is thought that 2 percent to 4 percent of people will have a seizure at some time. People who have epilepsy experience repeated seizure activity.

Text Continues Below



More information

The U.S. National Library of Medicine has more about seizures.

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-- Kevin McKeever

Copyright © 2008 ScoutNews, LLC. All rights reserved.
Last updated 6/8/2008

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SOURCE: University of Iowa, news release, June 8, 2008


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